Ggta1^tm1Ajfda
Targeted Allele Detail

Summary

• Symbol: Ggta1^tm1Ajfda
• Name: glycoprotein galactosyltransferase alpha 1, 3; targeted mutation 1, Anthony J F d'Apice
• MGI ID: MGI:6719253
• Synonyms: alpha1,3Gt^-, GalT^-, Ggta1^-
• Gene: Ggta1 Location: Chr2:35290191-35353243 bp, - strand Genetic Position: Chr2, 23.6 cM
• Alliance: Ggta1^tm1Ajfda page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:288220
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A flp site flanked neomycin resistance gene cassette was inserted into exon 9. RT-PCR experiments confirmed the absence of mRNA expression from this allele. (J:288220)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ggta1 Mutation: 81 strains or lines available

References

• Original: J:288220 Tearle RG, et al., The alpha-1,3-galactosyltransferase knockout mouse. Implications for xenotransplantation. Transplantation. 1996 Jan 15;61(1):13-9
• All: 7 reference(s)