Nup160^tm1Mdan
Targeted Allele Detail

Summary

• Symbol: Nup160^tm1Mdan
• Name: nucleoporin 160; targeted mutation 1, Maximiliano A D'Angelo
• MGI ID: MGI:6719493
• Synonyms: Nup160^f
• Gene: Nup160 Location: Chr2:90507559-90566672 bp, + strand Genetic Position: Chr2, 50.32 cM, cytoband E1
• Alliance: Nup160^tm1Mdan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:301567
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exon 4 was flanked by loxP sites. A self-excising neomycin selection cassette was also inserted. (J:301567)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nup160 Mutation: 64 strains or lines available

References

• Original: J:301567 Sakuma S, et al., Inhibition of Nuclear Pore Complex Formation Selectively Induces Cancer Cell Death. Cancer Discov. 2021 Jan;11(1):176-193
• All: 1 reference(s)