Agap3^tm1.1Ygi
Targeted Allele Detail

Summary

• Symbol: Agap3^tm1.1Ygi
• Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 3; targeted mutation 1.1, Shigeru Yanagi
• MGI ID: MGI:6719547
• Synonyms: Crag^WKO
• Gene: Agap3 Location: Chr5:24657175-24707045 bp, + strand Genetic Position: Chr5, 11.81 cM
• Alliance: Agap3^tm1.1Ygi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:307194
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Recombination removed the floxed segment. (J:307194)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Agap3 Mutation: 38 strains or lines available

References

• Original: J:307194 Huang J, et al., Critical role of CRAG, a splicing variant of centaurin-gamma3/AGAP3, in ELK1-dependent SRF activation at PML bodies. Sci Rep. 2019 Dec 27;9(1):20107
• All: 2 reference(s)