Trim23^em1Phua
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trim23^em1Phua
• Name: tripartite motif-containing 23; endonuclease-mediated mutation 1, Pingbo Huang
• MGI ID: MGI:6719577
• Gene: Trim23 Location: Chr13:104315305-104339880 bp, + strand Genetic Position: Chr13, 56.35 cM, cytoband D1
• Alliance: Trim23^em1Phua page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• Mutation details: CRISPR/cas mediated recombination inserted a 19 nt sequence (TAGATAGAATAGGAATTC) containing 3 stop codons in exon 2. (J:306292)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trim23 Mutation: 39 strains or lines available

References

• Original: J:306292 Cao X, et al., Opposing roles of E3 ligases TRIM23 and TRIM21 in regulation of ion channel ANO1 protein levels. J Biol Chem. 2021 May 3;:100738
• All: 1 reference(s)