Parp9^tm1.2Arte
Targeted Allele Detail

Summary

• Symbol: Parp9^tm1.2Arte
• Name: poly (ADP-ribose) polymerase family, member 9; targeted mutation 1.2, TaconicArtemis
• MGI ID: MGI:6721053
• Gene: Parp9 Location: Chr16:35759360-35792975 bp, + strand Genetic Position: Chr16, 25.43 cM
• Alliance: Parp9^tm1.2Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:306337
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 4 was floxed. Flp-mediated recombination removed the FRT-flanked puromycin resistance cassette. Cre-mediated recombination removed exon 4. (J:306337)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Parp9 Mutation: 92 strains or lines available

References

• Original: J:306337 Xing J, et al., Identification of poly(ADP-ribose) polymerase 9 (PARP9) as a noncanonical sensor for RNA virus in dendritic cells. Nat Commun. 2021 May 11;12(1):2681
• All: 1 reference(s)