Cox4i2^tm1.1Jlob
Targeted Allele Detail

Summary

• Symbol: Cox4i2^tm1.1Jlob
• Name: cytochrome c oxidase subunit 4I2; targeted mutation 1.1, Jose Lopez-Barneo
• MGI ID: MGI:6721093
• Synonyms: Cox4i2^fl
• Gene: Cox4i2 Location: Chr2:152596093-152606957 bp, + strand Genetic Position: Chr2, 75.41 cM, cytoband H2
• Alliance: Cox4i2^tm1.1Jlob page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:302384
• Parent Cell Line: iTL BF1 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 1 and 2 were floxed. Flp-mediated recombination removed the selection cassette. (J:302384)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cox4i2 Mutation: 13 strains or lines available

References

• Original: J:302384 Moreno-Dominguez A, et al., Acute O2 sensing through HIF2alpha-dependent expression of atypical cytochrome oxidase subunits in arterial chemoreceptors. Sci Signal. 2020 Jan 21;13(615)
• All: 1 reference(s)