Cib2tm1.1Zma
Targeted Allele Detail
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Symbol: |
Cib2tm1.1Zma |
Name: |
calcium and integrin binding family member 2; targeted mutation 1.1, Zubair M Ahmed |
MGI ID: |
MGI:6721389 |
Synonyms: |
Cib2F91S |
Gene: |
Cib2 Location: Chr9:54452078-54467502 bp, - strand Genetic Position: Chr9, 29.7 cM
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Alliance: |
Cib2tm1.1Zma page
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Germline Transmission: |
Earliest citation of germline transmission:
J:244562
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Not Specified) |
Mutations: |
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Insertion, Single point mutation
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Mutation details: The targeting construct modified exon 4 with the point mutation (c.272 T to C; ENSMUST00000041901) that results in the amino acid substitution of phenylalanine with serine. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted into intron 4.
(J:244562)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Cib2 Mutation: |
16 strains or lines available
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Original: |
J:244562 Giese APJ, et al., CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells. Nat Commun. 2017 Jun 29;8(1):43 |
All: |
1 reference(s) |
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