Qprt^{Gt(OST337946)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Qprt^{Gt(OST337946)Lex}
• Name: quinolinate phosphoribosyltransferase; gene trap OST337946, Lexicon Genetics
• MGI ID: MGI:6723745
• Gene: Qprt Location: Chr7:126706942-126721201 bp, - strand Genetic Position: Chr7, 69.33 cM
• Alliance: Qprt^{Gt(OST337946)Lex} page

Mutation origin

• Mutant Cell Line: OST337946
• Germline Transmission: Earliest citation of germline transmission: J:282516
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector
• Trapped gene association determined by genome coordinate overlap and strand. (J:282516)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Qprt Mutation: 20 strains or lines available

References

• Original: J:282516 Minhas PS, et al., Macrophage de novo NAD(+) synthesis specifies immune function in aging and inflammation. Nat Immunol. 2019 Jan;20(1):50-63
• All: 2 reference(s)