Tg(S100a4-flpo)3Lba
Transgene Detail

Summary

• Symbol: Tg(S100a4-flpo)3Lba
• Name: transgene insertion 3, Laurent Bartholin
• MGI ID: MGI:6723877
• Synonyms: Fsp1-Flpo
• Transgene: Tg(S100a4-flpo)3Lba Location: unknown
• Alliance: Tg(S100a4-flpo)3Lba page

Transgene origin

• Strain of Origin: mixed

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(S100a4-flpo)3Lba expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	S100a4 (MGI:1330282)

• Mutation details: The transgenic construct containing a ~3 kbp genomic DNA fragment of the mouse S100a4 promoter that drives gene expression in fibroblasts driving the mouse codon-optimized Flp (Flpo) site-specific recombinase was injected into oocytes (FVB B6 DBA2 mixed background) to obtain founder mice. Six founder lines (#3, #4, #9, #11, #17, and #35) were generated. The highest and fibroblast specific expression of flpo mRNA was observed in line 3 and used for the study. (J:286617)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	S100a4 (mouse) Summary of all recombinase alleles driven by S100a4. Comparative matrix view of recombinase activities Alliance mouse S100a4 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:286617 Cardot-Ruffino V, et al., Generation of an Fsp1 (fibroblast-specific protein 1)-Flpo transgenic mouse strain. Genesis. 2020 Mar 19;:e23359
• All: 2 reference(s)