Ar^em1(cre)Zsu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ar^em1(cre)Zsu
• Name: androgen receptor; endonuclease-mediated mutation 1, Zijie Sun
• MGI ID: MGI:6723948
• Synonyms: Ar^IRES-Cre
• Gene: Ar Location: ChrX:97192375-97366821 bp, + strand Genetic Position: ChrX, 42.82 cM
• Alliance: Ar^em1(cre)Zsu page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Ar^em1(cre)Zsu expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ar (MGI:88064)

• Mutation details: CRISPR/cas9 endonuclease mediated genome editing is used to insert IRES-cre expression cassette after the stop codon. (J:301558)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ar (mouse) Summary of all recombinase alleles driven by Ar. Comparative matrix view of recombinase activities Alliance mouse Ar gene page

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ar Mutation: 23 strains or lines available

References

• Original: J:301558 Lee DH, et al., Androgen action in cell fate and communication during prostate development at single-cell resolution. Development. 2021 Jan 11;148(1):dev196048
• All: 1 reference(s)