Prss28^em1Dhap
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prss28^em1Dhap
• Name: serine protease 28; endonuclease-mediated mutation 1, Pramod Dhakal
• MGI ID: MGI:6724044
• Synonyms: Prss28^-, Prss28^em1Tesp
• Gene: Prss28 Location: Chr17:25527620-25530850 bp, + strand Genetic Position: Chr17, 12.53 cM, cytoband A3.3
• Alliance: Prss28^em1Dhap page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 genome editing technology was used to generate a deletion of 876 base pairs that encompassed the start codon of the gene in exon 2 through exon 4. (J:307642)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Prss28 Mutation: 12 strains or lines available

References

• Original: J:307642 Dhakal P, et al., Generation and analysis of Prss28 and Prss29 deficient mice using CRISPR-Cas9 genome-editing. Mol Reprod Dev. 2021 May 10
• All: 1 reference(s)