Ndufa4l2^tm1.2Jlob
Targeted Allele Detail

Summary

• Symbol: Ndufa4l2^tm1.2Jlob
• Name: Ndufa4, mitochondrial complex associated like 2; targeted mutation 1.2, Jose Lopez-Barneo
• MGI ID: MGI:6724161
• Gene: Ndufa4l2 Location: Chr10:127350836-127353023 bp, + strand Genetic Position: Chr10, 74.51 cM
• Alliance: Ndufa4l2^tm1.2Jlob page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:302384
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was floxed. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 2. (J:302384)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ndufa4l2 Mutation: 9 strains or lines available

References

• Original: J:302384 Moreno-Dominguez A, et al., Acute O2 sensing through HIF2alpha-dependent expression of atypical cytochrome oxidase subunits in arterial chemoreceptors. Sci Signal. 2020 Jan 21;13(615)
• All: 1 reference(s)