Cd302^tm1.1Dnjh
Targeted Allele Detail

Summary

• Symbol: Cd302^tm1.1Dnjh
• Name: CD302 antigen; targeted mutation 1.1, Derek NJ Hart
• MGI ID: MGI:6724312
• Gene: Cd302 Location: Chr2:60082337-60114828 bp, - strand Genetic Position: Chr2, 34.5 cM
• Alliance: Cd302^tm1.1Dnjh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:301848
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct floxed the coding region in exon 1 an introduced a neomycin resistance cassette into intron 1. Cre-mediated recombination removed the coding region in exon 1 and the selection cassette. (J:301848)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd302 Mutation: 14 strains or lines available

References

• Original: J:301848 Lo TH, et al., Characterization of the Expression and Function of the C-Type Lectin Receptor CD302 in Mice and Humans Reveals a Role in Dendritic Cell Migration. J Immunol. 2016 Aug 1;197(3):885-98
• All: 1 reference(s)