Cdkn2a^{em3(cre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cdkn2a^{em3(cre/ERT2)Smoc}
• Name: cyclin dependent kinase inhibitor 2A; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
• MGI ID: MGI:6724360
• Synonyms: Cdkn2a^{em(Luc-tdTomato-CreERT2)Smoc}, Cdkn2a-Luc-2A-tdTomato-2A-CreERT2
• Gene: Cdkn2a Location: Chr4:89192710-89212856 bp, - strand Genetic Position: Chr4, 42.15 cM, cytoband C3-C6
• Alliance: Cdkn2a^{em3(cre/ERT2)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutation: Insertion
• Cdkn2a^{em3(cre/ERT2)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Cdkn2a (MGI:104738)

• Mutation details: A Luc-2A-tdTomato-2A-CreERT2-WPRE-pA cassette was fused in-frame with exon2 of Cdkn2a-201 transcript such that the exogenous proteins would be translated followed by the first 62aa of Cdkn2a. (J:238766)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cdkn2a (mouse) Summary of all recombinase alleles driven by Cdkn2a. Alliance mouse Cdkn2a gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdkn2a Mutation: 67 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 2 reference(s)