Tfpi2^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Tfpi2^tm1Dgen
• Name: tissue factor pathway inhibitor 2; targeted mutation 1, Deltagen
• MGI ID: MGI:6724439
• Gene: Tfpi2 Location: Chr6:3962595-3988919 bp, - strand Genetic Position: Chr6, 1.81 cM, cytoband A2
• Alliance: Tfpi2^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:301794
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct replaced exons 2 and 3 with an IRES, lacZ reporter gene, and neomycin resistance cassette. (J:301794)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tfpi2 Mutation: 15 strains or lines available

References

• Original: J:301794 Ali MN, et al., TFPI-2 Protects Against Gram-Negative Bacterial Infection. Front Immunol. 2018;9:2072
• All: 1 reference(s)