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Tfpi2tm1Dgen
Targeted Allele Detail
Summary
Symbol: Tfpi2tm1Dgen
Name: tissue factor pathway inhibitor 2; targeted mutation 1, Deltagen
MGI ID: MGI:6724439
Gene: Tfpi2  Location: Chr6:3962595-3988919 bp, - strand  Genetic Position: Chr6, 1.81 cM, cytoband A2
Alliance: Tfpi2tm1Dgen page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:301794
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe targeting construct replaced exons 2 and 3 with an IRES, lacZ reporter gene, and neomycin resistance cassette. (J:301794)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tfpi2 Mutation:  15 strains or lines available
References
Original:  J:301794 Ali MN, et al., TFPI-2 Protects Against Gram-Negative Bacterial Infection. Front Immunol. 2018;9:2072
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory