Pramel13^em1Dean
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pramel13^em1Dean
• Name: PRAME like 13; endonuclease-mediated mutation 1, Jurrien Dean
• MGI ID: MGI:6724472
• Synonyms: Pramef12^Null
• Gene: Pramel13 Location: Chr4:144118244-144135034 bp, - strand Genetic Position: Chr4, 77.98 cM
• Alliance: Pramel13^em1Dean page

Mutation origin

• Strain of Origin: (C57BL/6J x DBA/2J)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 2 deleted 49 bp. (J:282232)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pramel13 Mutation: 29 strains or lines available

References

• Original: J:282232 Wang Z, et al., Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice. Nat Commun. 2019 Nov 15;10(1):5196
• All: 1 reference(s)