Igs7^{em3(tetO-ERBB2*,-GFP,-cre)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Igs7^{em3(tetO-ERBB2*,-GFP,-cre)Smoc}
• Name: intergenic site 7; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
• MGI ID: MGI:6724583
• Synonyms: Igs7^{em1(tetO-ERBB2(exon20 insertion)-IRES-GFP-2A-Cre)Smoc}, Tigre-TetO-hERBB2*ex20ins-IRES-GFP-2A-Cre
• Gene: Igs7 Location: unknown Genetic Position: Chr9, Syntenic
• Alliance: Igs7^{em3(tetO-ERBB2*,-GFP,-cre)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Inserted expressed sequence, Recombinase, Reporter)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Igs7^{em3(tetO-ERBB2*,-GFP,-cre)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ERBB2 (2064)

  Erbb2

  (MGI:95410)

• Igs7^{em3(tetO-ERBB2*,-GFP,-cre)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  bacteria	tetO

• Mutation details: A tetO-ERBB2(exon20 insertion)-IRES-GFP-2A-Cre expression cassette was knocked into the TIGRE locus via CRISPR/Cas9 mediated recombination. (J:238766)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	tetO (bacteria) Summary of all recombinase alleles driven by tetO.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igs7 Mutation: 66 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)