Ins1^{em2(icre)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ins1^{em2(icre)Smoc}
• Name: insulin I; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
• MGI ID: MGI:6724586
• Synonyms: Ins1-Cre, Ins1^{em1(iCre)Smoc}
• Gene: Ins1 Location: Chr19:52252735-52253453 bp, + strand Genetic Position: Chr19, 46.76 cM
• Alliance: Ins1^{em2(icre)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Ins1^{em2(icre)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ins1 (MGI:96572)

• Mutation details: A iCre expression cassette was knocked into the Ins1 gene start codon site via CRISPR/Cas9 mediated recombination. (J:238766)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ins1 (mouse) Summary of all recombinase alleles driven by Ins1. Alliance mouse Ins1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ins1 Mutation: 46 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)