Cnga2^tm1.1Kob
Targeted Allele Detail

Summary

• Symbol: Cnga2^tm1.1Kob
• Name: cyclic nucleotide gated channel alpha 2; targeted mutation 1.1, Reiko Kobayakawa
• MGI ID: MGI:6725108
• Gene: Cnga2 Location: ChrX:71035455-71053824 bp, + strand Genetic Position: ChrX, 37.15 cM, cytoband A6
• Alliance: Cnga2^tm1.1Kob page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:307157
• Parent Cell Line: EGR-05 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 6 was floxed. An FRT flanked neomycin resistance cassette was inserted upstream of the loxP site 5' of exon 6 and breeding to a flp deleter strain excised the neomycin resistance cassette leaving this conditional ready allele. (J:219286, J:307157)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cnga2 Mutation: 17 strains or lines available

References

• Original: J:307157 Koike K, et al., Danger perception and stress response through an olfactory sensor for the bacterial metabolite hydrogen sulfide. Neuron. 2021 Jun;109:1-16
• All: 2 reference(s)