Prlr^{tm1.1(cre)Uboe}
Targeted Allele Detail

Summary

• Symbol: Prlr^{tm1.1(cre)Uboe}
• Name: prolactin receptor; targeted mutation 1.1, Ulrich Boehm
• MGI ID: MGI:6725828
• Synonyms: Prlr-IRES-Cre^neo-
• Gene: Prlr Location: Chr15:10177324-10349266 bp, + strand Genetic Position: Chr15, 5.23 cM
• Alliance: Prlr^{tm1.1(cre)Uboe} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:307688
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Prlr^{tm1.1(cre)Uboe} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Prlr (MGI:97763)

• Mutation details: An internal ribosomal entry site (IRES) and a Cre gene were inserted immediately after exon 10 of the gene. An FRT-flanked neomycin selection cassette was removed by mating to the FLPe recombinase deleted mice. (J:307688)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Prlr (mouse) Summary of all recombinase alleles driven by Prlr. Comparative matrix view of recombinase activities Alliance mouse Prlr gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prlr Mutation: 44 strains or lines available

References

• Original: J:307688 Kokay IC, et al., Analysis of prolactin receptor expression in the murine brain using a novel prolactin receptor reporter mouse. J Neuroendocrinol. 2018 Sep;30(9):e12634
• All: 10 reference(s)