Fgf9^tm1.2Zqch
Targeted Allele Detail

Summary

• Symbol: Fgf9^tm1.2Zqch
• Name: fibroblast growth factor 9; targeted mutation 1.2, Zhenqi Chen
• MGI ID: MGI:6726116
• Gene: Fgf9 Location: Chr14:58308543-58350311 bp, + strand Genetic Position: Chr14, 30.51 cM, cytoband D
• Alliance: Fgf9^tm1.2Zqch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:306390
• Parent Cell Line: SM1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct inserted a loxP site upstream of exon 2 and an FRT-flanked neomycin resistance cassette with a 3' loxP site downstream of exon 2. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 2. (J:306390)

Expression

In Mice Carrying this Mutation:	8 assay results
In Structures Affected by this Mutation:	10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgf9 Mutation: 17 strains or lines available

References

• Original: J:306390 Li R, et al., The Fibroblast Growth Factor 9 (Fgf9) Participates in Palatogenesis by Promoting Palatal Growth and Elevation. Front Physiol. 2021;12:653040
• All: 2 reference(s)