Wdhd1^em1Isyu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Wdhd1^em1Isyu
• Name: WD repeat and HMG-box DNA binding protein 1; endonuclease-mediated mutation 1, I-Shing Yu
• MGI ID: MGI:6726123
• Synonyms: Wdhd1^wk3
• Gene: Wdhd1 Location: Chr14:47478401-47514314 bp, - strand Genetic Position: Chr14, 24.6 cM
• Alliance: Wdhd1^em1Isyu page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• CRISPR-targeting inserted 5 bp and deleted 1 resulting in a stop codon creation (c.13delinsTGAGA). (J:306382)

Expression

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wdhd1 Mutation: 50 strains or lines available

References

• Original: J:306382 Fan HH, et al., Wdhd1 is essential for early mouse embryogenesis. Biochim Biophys Acta Mol Cell Res. 2021 May;1868(6):119011
• All: 1 reference(s)