Ms4a3^em2(cre)Fgnx
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ms4a3^em2(cre)Fgnx
• Name: membrane-spanning 4-domains, subfamily A, member 3; endonuclease-mediated mutation 2, Florent Ginhoux
• MGI ID: MGI:6726593
• Synonyms: Ms4a3^Cre, Ms4a3^em2(cre)Smoc
• Gene: Ms4a3 Location: Chr19:11606863-11618215 bp, - strand Genetic Position: Chr19, 8.47 cM, cytoband B
• Alliance: Ms4a3^em2(cre)Fgnx page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Ms4a3^em2(cre)Fgnx expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ms4a3 (MGI:2158468)

• Mutation details: An Ires-cre expression cassette was inserted into the 3' un-translated region (3'UTR) of the Ms4a3 gene by CRISPR-Cas9 technique in C57BL/6 zygotes. (J:284702)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ms4a3 (mouse) Summary of all recombinase alleles driven by Ms4a3. Comparative matrix view of recombinase activities Alliance mouse Ms4a3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ms4a3 Mutation: 17 strains or lines available

References

• Original: J:284702 Liu Z, et al., Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells. Cell. 2019 Sep 5;178(6):1509-1525.e19
• All: 12 reference(s)