Tg(Cldn11-cre/ERT2)151Tmak
Transgene Detail

Summary

• Symbol: Tg(Cldn11-cre/ERT2)151Tmak
• Name: transgene insertion 151, Taija Makinen
• MGI ID: MGI:6727043
• Synonyms: Cldn11-CreERT2
• Transgene: Tg(Cldn11-cre/ERT2)151Tmak Location: unknown
• Alliance: Tg(Cldn11-cre/ERT2)151Tmak page

Transgene origin

• Strain of Origin: C57BL/6NTac

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Cldn11-cre/ERT2)151Tmak expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Cldn11 (MGI:106925)

• Mutation details: The transgene contains the BAC RP23-128D19 with the cre recombinase fusion to the modified estrogen receptor (ERT2) inserted downstream of the translation initiation codon. Five transgenic founder lines were generated with one (line 151) showing specific cre activity in the lymphatic valve was established for further studies. (J:308453)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cldn11 (mouse) Summary of all recombinase alleles driven by Cldn11. Comparative matrix view of recombinase activities Alliance mouse Cldn11 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:308453 Ortsater H, et al., An inducible Cldn11-CreERT2 mouse line for selective targeting of lymphatic valves. Genesis. 2021
• All: 3 reference(s)