TgTn(pb-CAG-Gm614)#Cya
Transgene Detail

Summary

• Symbol: TgTn(pb-CAG-Gm614)#Cya
• Name: transgenic transposon concatemer, Cyagen Biosciences
• MGI ID: MGI:6727902
• Synonyms: Gm614 Tg, TgTn(pb-CAG-Gm614)#Cgen
• Transgene: TgTn(pb-CAG-Gm614)#Cya Location: unknown
• Alliance: TgTn(pb-CAG-Gm614)#Cya page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Transposon concatemer)
• Mutation: Transposon insertion
• TgTn(pb-CAG-Gm614)#Cya expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Gm614 (MGI:2685460)	mouse cDNA

• Mutation details: A piggyBac vector was used to insert the CAG promoter, mouse Gm614 cDNA and rat transforming growth factor beta receptor III (betaglycan) poly(A) signal sequence into the genome. An estimated five copies of the transgene were integrated. (J:307345)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:307345 He Y, et al., Gm614 Protects Germinal Center B Cells From Death by Suppressing Caspase-1 Transcription in Lupus-Prone Mice. Front Immunol. 2020;11:585726
• All: 1 reference(s)