Bmpr1b^tm1(cre)Ddg
Targeted Allele Detail

Summary

• Symbol: Bmpr1b^tm1(cre)Ddg
• Name: bone morphogenetic protein receptor, type 1B; targeted mutation 1, David D Ginty
• MGI ID: MGI:6728138
• Synonyms: Bmpr1b^T2a-Cre
• Gene: Bmpr1b Location: Chr3:141542897-141875186 bp, - strand Genetic Position: Chr3, 66.11 cM
• Alliance: Bmpr1b^tm1(cre)Ddg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:292971
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (C57BL/6 x 129)F1

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Bmpr1b^tm1(cre)Ddg expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Bmpr1b (MGI:107191)

• Mutation details: Using standard homologous recombination techniques in embryonic stem (ES) cells, targeting construct consisting of a T2a-Cre-TGA codon; Frt-PGK:NeoR-pA-Frt cassette was inserted immediately upstream of the stop codon in Bmpr1b. The neo cassette was left intact. (J:292971)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Bmpr1b (mouse) Summary of all recombinase alleles driven by Bmpr1b. Comparative matrix view of recombinase activities Alliance mouse Bmpr1b gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bmpr1b Mutation: 40 strains or lines available

References

• Original: J:292971 Sharma N, et al., The emergence of transcriptional identity in somatosensory neurons. Nature. 2020 Jan;577(7790):392-398
• All: 3 reference(s)