Myl9^tm1.1Mzhu
Targeted Allele Detail

Summary

• Symbol: Myl9^tm1.1Mzhu
• Name: myosin, light polypeptide 9, regulatory; targeted mutation 1.1, Min-Sheng Zhu
• MGI ID: MGI:6728819
• Gene: Myl9 Location: Chr2:156617373-156623578 bp, + strand Genetic Position: Chr2, 77.77 cM
• Alliance: Myl9^tm1.1Mzhu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:308237
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct floxed exon 2 and inserted an FRT-flanked neomycin resistance cassette into intron 2. Cre-mediated recombination removed exon 2 and the selection cassette. (J:308237)

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myl9 Mutation: 12 strains or lines available

References

• Original: J:308237 Sun J, et al., Distinct Roles of Smooth Muscle and Non-muscle Myosin Light Chain-Mediated Smooth Muscle Contraction. Front Physiol. 2020;11:593966
• All: 1 reference(s)