Uhrf1^tm1Smoc
Targeted Allele Detail

Summary

• Symbol: Uhrf1^tm1Smoc
• Name: ubiquitin-like, containing PHD and RING finger domains, 1; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6729206
• Synonyms: Uhrf^fl
• Gene: Uhrf1 Location: Chr17:56610405-56630486 bp, + strand Genetic Position: Chr17, 29.26 cM, cytoband D-E1
• Alliance: Uhrf1^tm1Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:304423
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting construct floxed exon 4. (J:304423)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Uhrf1 Mutation: 52 strains or lines available

References

• Original: J:304423 Gao ZJ, et al., Single-nucleotide methylation specifically represses type I interferon in antiviral innate immunity. J Exp Med. 2021 Mar 1;218(3)
• All: 9 reference(s)