Lyz2^em1(icre)Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lyz2^em1(icre)Gpt
• Name: lysozyme 2; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:6729910
• Synonyms: Lyz2-Cre
• Gene: Lyz2 Location: Chr10:117113446-117118177 bp, - strand Genetic Position: Chr10, 65.34 cM
• Alliance: Lyz2^em1(icre)Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Lyz2^em1(icre)Gpt expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lyz2 (MGI:96897)

• Mutation details: CRISPR-targeting introduced the improved cre recombinase gene into the N-terminus of the gene at the exon 1a translation initiation sequence. (J:293217)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lyz2 (mouse) Summary of all recombinase alleles driven by Lyz2. Alliance mouse Lyz2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lyz2 Mutation: 40 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 16 reference(s)