Tdrp^tm1Xwa
Targeted Allele Detail

Summary

• Symbol: Tdrp^tm1Xwa
• Name: testis development related protein; targeted mutation 1, Xuanchun Wang
• MGI ID: MGI:6730107
• Gene: Tdrp Location: Chr8:14002008-14025032 bp, - strand Genetic Position: Chr8, 6.44 cM
• Alliance: Tdrp^tm1Xwa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:307459
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked PGK-Neo cassette replaced exon 1. Western blot analysis confirmed the absence of protein in testes. (J:307459)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tdrp Mutation: 21 strains or lines available

References

• Original: J:307459 Mao S, et al., TDRP deficiency contributes to low sperm motility and is a potential risk factor for male infertility. Am J Transl Res. 2016;8(1):177-87
• All: 1 reference(s)