Mir148a^tm2942.2Arte
Targeted Allele Detail

Summary

• Symbol: Mir148a^tm2942.2Arte
• Name: microRNA 148a; targeted mutation 2942.2, TaconicArtemis
• MGI ID: MGI:6731011
• Synonyms: miR-148a^delta
• Gene: Mir148a Location: Chr6:51246792-51246890 bp, - strand Genetic Position: Chr6, 24.64 cM
• Alliance: Mir148a^tm2942.2Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:307366
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding sequence was flanked by loxP sites and an FRT-flanked neomycin resistance gene was inserted before the second loxP site. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination deleted the floxed coding region. (J:307366)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir148a Mutation: 5 strains or lines available

References

• Original: J:307366 Pracht K, et al., miR-148a controls metabolic programming and survival of mature CD19-negative plasma cells in mice. Eur J Immunol. 2021 May;51(5):1089-1109
• All: 1 reference(s)