Lcn9^em1(cre)Xys
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lcn9^em1(cre)Xys
• Name: lipocalin 9; endonuclease-mediated mutation 1, Xiao-yang Sun
• MGI ID: MGI:6731103
• Synonyms: Lcn9-Cre
• Gene: Lcn9 Location: Chr2:25713165-25715549 bp, + strand Genetic Position: Chr2, 18.15 cM, cytoband A3
• Alliance: Lcn9^em1(cre)Xys page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (No functional change, Recombinase)
• Mutation: Insertion
• Lcn9^em1(cre)Xys expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lcn9 (MGI:1924954)

• Mutation details: Using CRISPR/Cas9 technology, the TAG stop codon of the mouse Lcn9 was replaced by a 2A-NLS-Cre cassette. (J:308319)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lcn9 (mouse) Summary of all recombinase alleles driven by Lcn9. Comparative matrix view of recombinase activities Alliance mouse Lcn9 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lcn9 Mutation: 18 strains or lines available

References

• Original: J:308319 Gong QQ, et al., A novel mouse line with epididymal initial segment-specific expression of Cre recombinase driven by the endogenous Lcn9 promoter. PLoS One. 2021;16(7):e0254802
• All: 2 reference(s)