Foxl2^em1(cre)Gaof
Endonuclease-mediated Allele Detail

Summary

• Symbol: Foxl2^em1(cre)Gaof
• Name: forkhead box L2; endonuclease-mediated mutation 1, Fei Gao
• MGI ID: MGI:6739811
• Synonyms: Foxl2-Cre
• Gene: Foxl2 Location: Chr9:98837495-98840601 bp, + strand Genetic Position: Chr9, 51.41 cM, cytoband E4
• Alliance: Foxl2^em1(cre)Gaof page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Foxl2^em1(cre)Gaof expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Foxl2 (MGI:1349428)

• Mutation details: A Cre-P2A expression cassette was knocked into the Foxg1 gene start codon site via CRISPR/Cas9 mediated recombination. (J:292639)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Foxl2 (mouse) Summary of all recombinase alleles driven by Foxl2. Comparative matrix view of recombinase activities Alliance mouse Foxl2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Foxl2 Mutation: 15 strains or lines available

References

• Original: J:292639 Cen C, et al., Inactivation of Wt1 causes pre-granulosa cell to steroidogenic cell transformation and defect of ovary development. Biol Reprod. 2020 Jun 23;103(1):60-69
• All: 3 reference(s)