Del(1)1Smun
Transgene Detail

Summary

• Symbol: Del(1)1Smun
• Name: deletion, Chr 1, Stefan Mundlos
• MGI ID: MGI:6740196
• Synonyms: Del1Smun, Del(27)
• Transgene: Del(1)1Smun Location: unknown Genetic Position: Chr1, Syntenic
• Alliance: Del(1)1Smun page

Mutation origin

• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intergenic deletion
• Del(1)1Smun involves 1 genes/genome features (Gm29348) View all
• Mutation details: The deletion is within chr 1;122,441,093-122,831,023 (mm9) telomeric to En1 was deleted to mimic the 27 kb deletion 200 kb centormeric to En1 (chr2:118,504,360-118,897,678; hg38) found in a patient with severe congenital limb malformation. (J:306235)

Expression

In Mice Carrying this Mutation:	29 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:306235 Allou L, et al., Non-coding deletions identify Maenli lncRNA as a limb-specific En1 regulator. Nature. 2021 Apr;592(7852):93-98
• All: 2 reference(s)