Trpm5^{tm1.1(cre)Uboe}
Targeted Allele Detail

Summary

• Symbol: Trpm5^{tm1.1(cre)Uboe}
• Name: transient receptor potential cation channel, subfamily M, member 5; targeted mutation 1.1, Ulrich Boehm
• MGI ID: MGI:6755459
• Synonyms: TRPM5-IC, TRPM5-IRES-Cre^neo-
• Gene: Trpm5 Location: Chr7:142625266-142648379 bp, - strand Genetic Position: Chr7, 88.11 cM
• Alliance: Trpm5^{tm1.1(cre)Uboe} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:263255
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Trpm5^{tm1.1(cre)Uboe} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Trpm5 (MGI:1861718)

• Mutation details: An IRES-Cre-FRT-neo-FRT cassette was inserted into the exon 25 of mouse TRPM5 gene. The neo cassette was removed by germline flp mediated recombination. (J:263255)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Trpm5 (mouse) Summary of all recombinase alleles driven by Trpm5. Comparative matrix view of recombinase activities Alliance mouse Trpm5 gene page

Expression

In Mice Carrying this Mutation:

17 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trpm5 Mutation: 57 strains or lines available

References

• Original: J:263255 Kusumakshi S, et al., A Binary Genetic Approach to Characterize TRPM5 Cells in Mice. Chem Senses. 2015 Jul;40(6):413-25
• All: 5 reference(s)