Piezo1^{tm2(cre/ERT2)Smoc}
Targeted Allele Detail

Summary

• Symbol: Piezo1^{tm2(cre/ERT2)Smoc}
• Name: piezo-type mechanosensitive ion channel component 1; targeted mutation 2, Shanghai Model Organisms Center
• MGI ID: MGI:6758043
• Synonyms: Piezo1-CreERT2, Piezo1^{tm2(CreERT2)Smoc}
• Gene: Piezo1 Location: Chr8:123208437-123278068 bp, - strand Genetic Position: Chr8, 71.31 cM
• Alliance: Piezo1^{tm2(cre/ERT2)Smoc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238766
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Piezo1^{tm2(cre/ERT2)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Piezo1 (MGI:3603204)

• Mutation details: This tamoxifen-inducing Piezo1-CreERT2 tool mouse model was established by inserting a 2A-CreERT2 co-expression cassette into the Piezo1 gene stop codon site . (J:238766)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Piezo1 (mouse) Summary of all recombinase alleles driven by Piezo1. Alliance mouse Piezo1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Piezo1 Mutation: 89 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)