Ptf1a^{em1(cre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ptf1a^{em1(cre/ERT2)Smoc}
• Name: pancreas specific transcription factor, 1a; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6758049
• Synonyms: Ptf1a-CreERT2, Ptf1a^{em1(CreERT2-WPRE-pA)Smoc}
• Gene: Ptf1a Location: Chr2:19450474-19452312 bp, + strand Genetic Position: Chr2, 13.37 cM, cytoband A2
• Alliance: Ptf1a^{em1(cre/ERT2)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Ptf1a^{em1(cre/ERT2)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ptf1a (MGI:1328312)

• A CreERT2-WPRE-pA expression cassette was knocked into the Ptf1a gene start codon site. (J:238766)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ptf1a (mouse) Summary of all recombinase alleles driven by Ptf1a. Alliance mouse Ptf1a gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptf1a Mutation: 31 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)