Anxa10^{tm1.1(cre/ERT2)Dstan}
Targeted Allele Detail

Summary

• Symbol: Anxa10^{tm1.1(cre/ERT2)Dstan}
• Name: annexin A10; targeted mutation 1.1, Daniel E Stange
• MGI ID: MGI:6758084
• Synonyms: Anxa10-CreER^T2
• Gene: Anxa10 Location: Chr8:62510076-62576184 bp, - strand Genetic Position: Chr8, 31.55 cM
• Alliance: Anxa10^{tm1.1(cre/ERT2)Dstan} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:309130
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Anxa10^{tm1.1(cre/ERT2)Dstan} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Anxa10 (MGI:1347090)

• Mutation details: An IRESCreERT2 and a PGK-Neo cassette flanked by FRT site were inserted after the stop codon of the last exon 12 of the Anxa10 gene by homologous recombination in C57BL/6 ES cells. The PGK-Neo cassette was removed by crossing to FLP expressing mice. (J:309130)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Anxa10 (mouse) Summary of all recombinase alleles driven by Anxa10. Comparative matrix view of recombinase activities Alliance mouse Anxa10 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Anxa10 Mutation: 30 strains or lines available

References

• Original: J:309130 Seidlitz T, et al., Mouse Models of Human Gastric Cancer Subtypes With Stomach-Specific CreERT2-Mediated Pathway Alterations. Gastroenterology. 2019 Dec;157(6):1599-1614.e2
• All: 2 reference(s)