Tg(Mc3r-cre)#Cone
Transgene Detail

Summary

• Symbol: Tg(Mc3r-cre)#Cone
• Name: transgene insertion, Roger D Cone
• MGI ID: MGI:6758196
• Synonyms: MC3R-Cre
• Transgene: Tg(Mc3r-cre)#Cone Location: unknown
• Alliance: Tg(Mc3r-cre)#Cone page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Mc3r-cre)#Cone expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Mc3r (MGI:96929)

• Mutation details: The transgene consists of bacterial artificial chromosome (BAC RP24-181G19) DNA constructs expressing Cre recombinase under the control of the MC3R promoter. Multiple funder lines were created. However, the line numbers were not indicated. The line showing faithful cre activities in ARC, PVT, nucleus accumbens, and ventral tegmental area was used for the studies. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:287574)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Mc3r (mouse) Summary of all recombinase alleles driven by Mc3r. Alliance mouse Mc3r gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:287574 Ghamari-Langroudi M, et al., Regulation of energy rheostasis by the melanocortin-3 receptor. Sci Adv. 2018 Aug;4(8):eaat0866
• All: 4 reference(s)