Usp26^tm1Smoc
Targeted Allele Detail

Summary

• Symbol: Usp26^tm1Smoc
• Name: ubiquitin specific peptidase 26; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6758249
• Gene: Usp26 Location: ChrX:50842836-50890110 bp, - strand Genetic Position: ChrX, 28.31 cM
• Alliance: Usp26^tm1Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:277424
• Parent Cell Line: PRX-129S6 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct replaced exon 9 with an FRT-flanked neomycin resistance cassette with a 3' loxP site. (J:277424)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp26 Mutation: 6 strains or lines available

Notes

EXS cells = SCR012

References

• Original: J:277424 Tian H, et al., Disruption of ubiquitin specific protease 26 gene causes male subfertility associated with spermatogenesis defects in mice. Biol Reprod. 2019 Apr 1;100(4):1118-1128
• All: 1 reference(s)