Tg(Lyve1-cre/ERT2)49Rtem
Transgene Detail

Summary

• Symbol: Tg(Lyve1-cre/ERT2)49Rtem
• Name: Transgene insertion 49, Richard Tempero
• MGI ID: MGI:6758737
• Synonyms: Lyve1CreERT2-49
• Transgene: Tg(Lyve1-cre/ERT2)49Rtem Location: unknown
• Alliance: Tg(Lyve1-cre/ERT2)49Rtem page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Lyve1-cre/ERT2)49Rtem expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lyve1 (MGI:2136348)

• Mutation details: By using recombineering bacterial strain, the transgene with cre/ERT2 was inserted into a bacterial artificial chromosome (BAC: RP23 332E15) containing the mouse Lyve1 promoter and gene. Three strains transmitted the transgene in the germline after crossing with C57BL/6. Line 49 demonstrated the greatest and most reliable tdT induction efficiency and was used in all studies. (J:309509)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lyve1 (mouse) Summary of all recombinase alleles driven by Lyve1. Comparative matrix view of recombinase activities Alliance mouse Lyve1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:309509 Connor AL, et al., Lymphatic endothelial lineage assemblage during corneal lymphangiogenesis. Lab Invest. 2016 Mar;96(3):270-82
• All: 2 reference(s)