Plin5^tm1Macl
Targeted Allele Detail

Summary

• Symbol: Plin5^tm1Macl
• Name: perilipin 5; targeted mutation 1, Malin C Levin
• MGI ID: MGI:6758997
• Synonyms: Plin5^Hyg, Plin5^KO
• Gene: Plin5 Location: Chr17:56418601-56424596 bp, - strand Genetic Position: Chr17, 29.16 cM
• Alliance: Plin5^tm1Macl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:286482
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 4-6 were replaced with a hygromycin resistance gene flanked by FRT5 sites via homologous recombination.

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plin5 Mutation: 22 strains or lines available

References

• Original: J:286482 Drevinge C, et al., Perilipin 5 is protective in the ischemic heart. Int J Cardiol. 2016 Sep 15;219:446-54
• All: 2 reference(s)