Tg(Atoh1-cre/ERT2)45Fmr
Transgene Detail

Summary

• Symbol: Tg(Atoh1-cre/ERT2)45Fmr
• Name: transgene insertion 45, Filippo M Rijli
• MGI ID: MGI:6759845
• Synonyms: Atoh1(45)::Cre, Atoh1::CreERT2
• Transgene: Tg(Atoh1-cre/ERT2)45Fmr Location: unknown
• Alliance: Tg(Atoh1-cre/ERT2)45Fmr page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Atoh1-cre/ERT2)45Fmr expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Atoh1 (MGI:104654)

• Mutation details: The transgene consists of a 1.7 kb enhancer of Atoh1 and beta-globin minimal promotor followed by CreERT2-SV40pA. One founder (#45) shows cre activity in absence of tamoxifen was established. (J:306314)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Atoh1 (mouse) Summary of all recombinase alleles driven by Atoh1. Comparative matrix view of recombinase activities Alliance mouse Atoh1 gene page
User Notes:	Additional information submitted by the research community Additional information submitted by the research community Although the transgene contained cre/ERT2, the cre activity was observed in absence of tamoxifen.

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:306314 Maheshwari U, et al., Postmitotic Hoxa5 Expression Specifies Pontine Neuron Positional Identity and Input Connectivity of Cortical Afferent Subsets. Cell Rep. 2020 Jun 16;31(11):107767
• All: 1 reference(s)