Lrrk1^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Lrrk1^m1Btlr
• Name: leucine-rich repeat kinase 1; mutation 1, Bruce Beutler
• MGI ID: MGI:6760630
• Synonyms: Lrrk1^I1383N
• Gene: Lrrk1 Location: Chr7:65908493-66038089 bp, - strand Genetic Position: Chr7, 35.57 cM
• Alliance: Lrrk1^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A-to-T point mutation that results in the amino acid substitution of isoleucine with asparagine at position 1383 (p.I1383N). (J:309727)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lrrk1 Mutation: 78 strains or lines available

References

• Original: J:309727 Rios JJ, et al., Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice. J Bone Miner Res. 2021 Aug;36(8):1548-1565
• All: 1 reference(s)