Tg(Mcpt8-icre/ERT2)#Hkar
Transgene Detail

Summary

• Symbol: Tg(Mcpt8-icre/ERT2)#Hkar
• Name: transgene insertion, Hajime Karasuyama
• MGI ID: MGI:6760637
• Synonyms: Mcpt8^iCreERT2
• Transgene: Tg(Mcpt8-icre/ERT2)#Hkar Location: unknown
• Alliance: Tg(Mcpt8-icre/ERT2)#Hkar page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Mcpt8-icre/ERT2)#Hkar expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Mcpt8 (MGI:1261780)

• Mutation details: The transgene was generated by a bacterial recombineering technique to replace the first exon of the mouse Mcpt8 gene in a BAC clone RP23-16G10 with an icre/ERT2 expression cassette. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:284409)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Mcpt8 (mouse) Summary of all recombinase alleles driven by Mcpt8. Comparative matrix view of recombinase activities Alliance mouse Mcpt8 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:284409 Yoshikawa S, et al., Pivotal role of STIM2, but not STIM1, in IL-4 production by IL-3-stimulated murine basophils. Sci Signal. 2019 Apr 9;12(576)
• All: 1 reference(s)