Dmp1^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Dmp1^m1Btlr
• Name: dentin matrix protein 1; mutation 1, Bruce Beutler
• MGI ID: MGI:6760638
• Synonyms: Dmp1^L10P
• Gene: Dmp1 Location: Chr5:104350479-104361968 bp, + strand Genetic Position: Chr5, 50.61 cM
• Alliance: Dmp1^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A-to-T point mutation that results in the amino acid substitution of leucine with proline at position 10 (p.L10P). (J:309727)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dmp1 Mutation: 42 strains or lines available

References

• Original: J:309727 Rios JJ, et al., Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice. J Bone Miner Res. 2021 Aug;36(8):1548-1565
• All: 1 reference(s)