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Rem1tm1Jsat
Targeted Allele Detail
Summary
Symbol: Rem1tm1Jsat
Name: rad and gem related GTP binding protein 1; targeted mutation 1, Jonathan Satin
MGI ID: MGI:6760672
Synonyms: Rem-
Gene: Rem1  Location: Chr2:152468928-152477111 bp, + strand  Genetic Position: Chr2, 75.41 cM, cytoband H2
Alliance: Rem1tm1Jsat page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:309872
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was replaced with a lacZ expressing cassette and an FRT-flanked neomycin selection gene. Immunoblot analysis confirmed the complete absence of protein expression in cardiac muscle of homozygous mutant mice. (J:309872)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rem1 Mutation:  23 strains or lines available
References
Original:  J:309872 Magyar J, et al., Rem-GTPase regulates cardiac myocyte L-type calcium current. Channels (Austin). 2012 May-Jun;6(3):166-73
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory