Tg(Wnt5a-cre/ERT2)#Jwng
Transgene Detail

Summary

• Symbol: Tg(Wnt5a-cre/ERT2)#Jwng
• Name: transgene insertion, Jianbo Wang
• MGI ID: MGI:6760675
• Synonyms: Wnt5aCreER
• Transgene: Tg(Wnt5a-cre/ERT2)#Jwng Location: unknown
• Alliance: Tg(Wnt5a-cre/ERT2)#Jwng page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Wnt5a-cre/ERT2)#Jwng expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Wnt5a (MGI:98958)

• Mutation details: The transgene was generated by modifying BAC RP23-357M9 such that CreERT2 cassette into Wnt5a genomic region to replace the entire exon 2. Two lines were generated with virtually identical expression patterns. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:284141)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Wnt5a (mouse) Summary of all recombinase alleles driven by Wnt5a. Comparative matrix view of recombinase activities Alliance mouse Wnt5a gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:284141 Li D, et al., Planar cell polarity signaling regulates polarized second heart field morphogenesis to promote both arterial and venous pole septation. Development. 2019 Oct 9;146(20):dev181719
• All: 1 reference(s)