Uxs1^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Uxs1^m1Btlr
• Name: UDP-glucuronate decarboxylase 1; mutation 1, Bruce Beutler
• MGI ID: MGI:6761388
• Synonyms: Uxs1^N276S
• Gene: Uxs1 Location: Chr1:43786126-43866960 bp, - strand Genetic Position: Chr1, 23.46 cM
• Alliance: Uxs1^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis produced a T-to-C point mutation that results in the amino acid substitution of asparagine with serine at position 276 (p.N276S). (J:309727)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Uxs1 Mutation: 28 strains or lines available

References

• Original: J:309727 Rios JJ, et al., Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice. J Bone Miner Res. 2021 Aug;36(8):1548-1565
• All: 2 reference(s)