Xylt1^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Xylt1^m2Btlr
• Name: xylosyltransferase 1; mutation 2, Bruce Beutler
• MGI ID: MGI:6761399
• Synonyms: Xylt1^H353R
• Gene: Xylt1 Location: Chr7:116980214-117266853 bp, + strand Genetic Position: Chr7, 62.93 cM
• Alliance: Xylt1^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T-to-A point mutation that results in the amino acid substitution of histidine with arginine at position 353 (p.H353R). (J:309727)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Xylt1 Mutation: 38 strains or lines available

References

• Original: J:309727 Rios JJ, et al., Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice. J Bone Miner Res. 2021 Aug;36(8):1548-1565
• All: 1 reference(s)